We believe that it should be possible to resolve this issue fairly easily with the right data analysis (see discussion on blog entry from June 2008). The “New” Prostate Cancer InfoLink is neutral. William Catalona and colleagues, believes that PSA velocity is a strong indicator of risk for aggressive prostate cancer, and that men with a rapidly rising PSA are at greater risk for aggressive disease that needs treatment than men with a slowly rising PSA.Īnother group, represented by Andrew Vickers and colleagues, believes that PSA velocity is irrelevant to prostate cancer risk by comparison with other available data, and that we don’t need the PSA velocity to tell us who is at risk because we already know. There are two very different theories about this. Enjoy! Does PSA Velocity Affect Prostate Cancer Risk? There is a PSA velocity calculator available on a University of California web site.
It is way too complicated and may not even matter that much. We aren’t going to even try to get into all the theories about the “right” way to measure PSA velocity. However, we can’t tell precisely because we do not know his PSA level in April 2010. This would appear to be approximatelyģ.6 – 1.9 = 1.7 ng/ml over 12 months = 1.36 ng/ml per year. In the example given above, an alternative way to look at the data is to ask what this patient’s PSA velocity has been over the past year. In other words, your PSA velocity depends on the PSA values you have available and over what length of time. On the other hand, if we assume your PSA was still stable at 1.9 ng/ml, then your PSA velocity isģ.6 – 1.9 = 1.7 ng/ml over 15 months = 1.36 ng/ml per year. If we make the assumption that your PSA was stable at the initial value of 1.4 ng/ml, then your PSA velocity is an increase ofģ.6 – 1.4 = 2.2 ng/ml over 39 months = 0.68 ng/ml per year. Let’s say you have the following PSA values over time: Basically, PSA velocity is the rate at which your PSA level increases from year to year.
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